Complete nucleotide sequence of the gene encoding rat cytochrome c oxidase subunit IV

Recently we have isolated the genomic clones of rat cytochrome c oxidase subunit IV and determined the structural organization of the gene (1). Here we report the complete nucleotide sequence of the gene encoding rat cytochrome c oxidase subunit IV for the record. The rat cytochrome c oxidase subunit IV gene is composed of 6,106 nucleotides and is organized in five exons (exon 1; 44 bp, exon 2; 74 bp, exon 3; 168 bp, exon 4; 132 bp, exon 5; 235 bp) and four introns (intron 1; 969 bp, intron 2; 3,302 bp, intron 3; 391 bp and intron 4; 791 bp). The 5'-flanking region of the gene possesses several characteristic features common to a group of house-keeping genes as described elsewhere (1).